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Accurately Quantify Cellular GSH/GSSG Redox with SEMKUR IM
Accurately Quantify Cellular GSH/GSSG Redox with SEMKUR IM - Image 2

Accurately Quantify Cellular GSH/GSSG Redox with SEMKUR IM

Price range: $200.00 through $325.00

SemKur is a non-toxic, cell-permeable fluorescent redox indicator optimized for live-cell imaging of glutathione (GSH/GSSG) ratios. SemKur utilizes a reversible disulfide exchange mechanism to enable quantitative detection of oxidative stress and intracellular redox dynamics in real time. Its non-toxic nature and lack of photobleaching supports longitudinal fluorescence imaging without inducing stress-related artifacts, making it ideal for applications in cell viability assays, redox biology, disease modeling, and drug toxicity screening. SemKur is validated across multiple cell types, including neuronal, immune, epithelial, and iPSC-derived cultures.

Explore thiol dynamics with SemKur’s robust, cell-permeable DSSQ chemistry.

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Description

SEMKUR uses native and physiologically relevant thiol-disulfide exchange chemistry to enable measurement of cellular redox homeostasis and physiology in a native state.

  • Dynamic Redox Resolution – captures real-time redox dynamics (GSH/GSSG ratio) in response to drugs, stressors, or stimuli, to reveal transient signaling events.
  • Reversible Disulfide Exchange – SemKur reflects true redox buffering—not just GSH levels.
  • Non-Toxic and Live-Cell Compatible – ideal for extended, artifact-free imaging.

 

https://vividmicroscopy.com/imaging/

Additional information

Weight 1 kg
Dimensions 7 × 6 × 5 cm
Quantity

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